GLA
Description
The GLA gene, located on chromosome X, encodes for the enzyme alpha-galactosidase A. This enzyme plays a vital role in the lysosome, a cellular organelle responsible for breaking down complex molecules. Alpha-galactosidase A specifically breaks down a sugar molecule called globotriaosylceramide (Gb3). Mutations in the GLA gene can lead to a buildup of Gb3, causing a range of health issues.
Associated Diseases
Did you know?
Fabry disease, caused by GLA gene mutations, is a rare genetic disorder that primarily affects males.
