GPR89A
Description
The GPR89A (G protein-coupled receptor 89A) is a protein-coding gene located on chromosome 1.
GPR89A is a voltage-dependent anion channel essential for the acidification and proper function of the Golgi apparatus. It contributes to counter-ion conductance, playing a crucial role in lymphocyte development likely by acting as a RABL3 effector in hematopoietic cells.
GPR89A is also known as GPHR, GPR89, GPR89B, SH120, UNQ192.
Associated Diseases
- Okt4 epitope deficiency
- combined immunodeficiency with skin granulomas
- 22q11.2 deletion syndrome
- immunodeficiency 19
- immunodeficiency 18
- trigonocephaly
