PLEKHB2

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Description

The PLEKHB2 (pleckstrin homology domain containing B2) is a protein-coding gene located on chromosome 2.

PLEKHB2 gene encodes a protein called Pleckstrin homology domain-containing family B member 2 in humans.

Plays a role in the movement of recycling endosomes back towards the cell center (retrograde transport).

PLEKHB2 is also known as EVT2.

Associated Diseases

• nonpapillary renal cell carcinoma
• spindle cell hemangioma
• bipolar disorder
• Alzheimer disease
• cancer