PNCK
Description
The PNCK (pregnancy up-regulated nonubiquitous CaM kinase) is a protein-coding gene located on chromosome X.
PNCK is a calcium/calmodulin-dependent protein kinase that participates in a proposed calcium-triggered signaling cascade. It has been shown to phosphorylate CREB1 and SYN1/synapsin I in vitro, and is believed to activate CAMK1.
PNCK is also known as BSTK3, CaMK1b.
Associated Diseases
- creatine transporter deficiency
- cerebral creatine deficiency syndrome
- nonpapillary renal cell carcinoma
- schizophrenia 15
- Phelan-McDermid syndrome
- cancer
- breast cancer
- colorectal cancer
- Bartsocas-Papas syndrome 1
- cervical squamous intraepithelial neoplasia
