PPP2R5B

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Description

The PPP2R5B (protein phosphatase 2 regulatory subunit B'beta) is a protein-coding gene located on chromosome 11.

PPP2R5B gene encodes the beta isoform of the regulatory subunit B56 of protein phosphatase 2A (PP2A). PP2A is a major serine/threonine phosphatase involved in regulating cell growth and division. The B regulatory subunit influences substrate specificity and catalytic activity of PP2A.

PPP2R5B is also known as B56B, B56beta, PR61B.

Associated Diseases

• cancer
• endometrial cancer
• ovarian cancer
• breast cancer