RALGAPB
Description
The RALGAPB (Ral GTPase activating protein non-catalytic subunit beta) is a protein-coding gene located on chromosome 20.
RALGAPB is a non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes. These complexes act as GTPase activators for the Ras-like small GTPases RALA and RALB.
RALGAPB is also known as KIAA1219, RalGAPbeta.
Associated Diseases
- septooptic dysplasia
- hypoparathyroidism, familial isolated, 2
- isolated hyperchlorhidrosis
- familial hyperaldosteronism type II
- breast cancer
- Alzheimer disease
