RB1 : RB transcriptional corepressor 1
The RB1 Gene: A Guardian of Cell Growth and Tumor Suppression
Description:
The RB1 gene holds the blueprint for a vital protein called pRB, which plays a critical role as a tumor suppressor. This gatekeeper ensures proper cell growth and prevents uncontrolled cell division, safeguarding against the development of tumors.
Associated Diseases:
Mutations in the RB1 gene can lead to several diseases, including:
- Retinoblastoma: A rare eye cancer that typically affects young children.
- Osteosarcoma: A bone cancer that predominantly affects adolescents and young adults.
- Lung cancer: Mutations in RB1 have been associated with certain types of lung cancer.
Did you Know ?
Around 1 in 15,000 newborns is affected by retinoblastoma, making it the most common eye cancer in children.
