RNF130
Description
The RNF130 (ring finger protein 130) is a protein-coding gene located on chromosome 5.
RNF130 potentially plays a role in the programmed death of blood-forming cells. It functions as an E3 ubiquitin-protein ligase, which attaches ubiquitin molecules to target proteins, potentially influencing their fate and function.
RNF130 is also known as G1RP, G1RZFP, GOLIATH, GP.
Associated Diseases
- cholesterol-ester transfer protein deficiency
- hypertriglyceridemia 2
- pancreatic triacylglycerol lipase deficiency
- homozygous familial hypercholesterolemia
- sitosterolemia
- chylomicron retention disease
