RPRM

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Description

The RPRM (reprimo, TP53 dependent G2 arrest mediator homolog) is a protein-coding gene located on chromosome 2.

RPRM may play a role in regulating the cell cycle by inducing G2 arrest, a process that depends on the p53 protein. It is thought to achieve this by hindering the activity of CDK1 (cyclin-dependent kinase 1) and preventing the CDC2 cyclin B1 complex from entering the nucleus.

RPRM is also known as REPRIMO.

Associated Diseases

• osteoarthritis
• cancer
• pituitary tumor
• breast cancer
• colorectal cancer