RSAD1
Description
The RSAD1 (radical S-adenosyl methionine domain containing 1) is a protein-coding gene located on chromosome 17.
RSAD1 (Radical S-adenosyl methionine domain containing 1) is a protein encoded by the RSAD1 gene in humans.
RSAD1 may function as a heme chaperone, binding to heme. While its bacterial homologs lack oxygen-independent coproporphyrinogen-III oxidase activity, RSAD1 binds a single [4Fe-4S] cluster coordinated with 3 cysteine residues and an exchangeable S-adenosyl-L-methionine.
RSAD1 is also known as HemW.
Associated Diseases
- Parkinson disease
- lysosomal storage disease
- Alzheimer disease
- multiple sclerosis
- 46,XX ovotesticular disorder of sex development
- testicular agenesis
- 46,XY sex reversal 3
- pigmented nodular adrenocortical disease, primary, 3
- 46,XY complete gonadal dysgenesis
