SAMD4B

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Description

The SAMD4B (sterile alpha motif domain containing 4B) is a protein-coding gene located on chromosome 19.

SAMD4B is a protein encoded by the SAMD4B gene in humans. It contains a sterile alpha motif domain.

SAMD4B acts as a transcriptional repressor, suppressing the activity of transcription factors like AP-1, p53/TP53, and CDKN1A when overexpressed.

SAMD4B is also known as SMGB, Smaug2.

Associated Diseases

• cancer
• pancreatic ductal adenocarcinoma
• colorectal cancer