SCFD1
Description
The SCFD1 (sec1 family domain containing 1) is a protein-coding gene located on chromosome 14.
Sec1 family domain-containing protein 1 (SCFD1) is a protein encoded by the SCFD1 gene in humans. It has been shown to interact with USO1.
SCFD1 plays a role in SNARE-pin assembly and the transport of vesicles from the Golgi apparatus back to the endoplasmic reticulum (ER). This transport process is facilitated through its interaction with the COG4 protein, a component of the COG complex.
SCFD1 is also known as C14orf163, RA410, SLY1, SLY1P, STXBP1L2.
Associated Diseases
- amyotrophic lateral sclerosis
- urinary bladder cancer
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- hemoglobin D disease
- delta-beta-thalassemia
- dominant beta-thalassemia
- hemoglobin C-beta-thalassemia syndrome
- hemoglobin E-beta-thalassemia syndrome
- alpha-thalassemia-myelodysplastic syndrome
- hemoglobin E disease
