SCRN3
Description
The SCRN3 (secernin 3) is a protein-coding gene located on chromosome 2.
Secernin-3 (SCRN3) is a protein encoded by the human SCRN3 gene. It belongs to the peptidase C69 family and the secernin subfamily. As a part of this family, the protein is predicted to enable cysteine-type exopeptidase activity and dipeptidase activity, as well as be involved in proteolysis. It is ubiquitously expressed in the brain, thyroid, and 25 other tissues. Additionally, SCRN3 is conserved in a variety of species, including mammals, birds, fish, amphibians, and invertebrates. SCRN3 is predicted to be an integral component of the cytoplasm.
== Gene == SCRN3 is also commonly known as FLJ23142 and SES3.
=== Locus ===
Homo sapiens secernin-3 (SCRN3) is a protein-coding gene. It can be found on chromosome 2, with its specific location being 2q31.1, on the '+' strand. The gene is 33,846 base pairs long and contains 8 exons.
SCRN3 is also known as SES3.
Associated Diseases
- early-onset non-syndromic cataract
- hereditary hyperferritinemia with congenital cataracts
- isolated ectopia lentis
- cataract 38
- cataract 13 with adult I phenotype
- cataract
