SCX
Description
The SCX (scleraxis bHLH transcription factor) is a protein-coding gene located on chromosome 8.
SCX is a human gene.
SCX plays a crucial role in the early development of mesoderm, the germ layer that gives rise to muscles, bones, and blood. It also has a later role in the development of chondrogenic lineages, which are cells that form cartilage, a type of connective tissue found in joints.
SCX is also known as SCXA, SCXB, bHLHa48.
Associated Diseases
- syndactyly type 1
- syndactyly type 4
- syndactyly type 3
- familial idiopathic steroid-resistant nephrotic syndrome
- syndactyly type 5
- polysyndactyly 4
- mesoaxial synostotic syndactyly with phalangeal reduction
- brachydactyly-syndactyly syndrome
- brachydactyly type A2
- polydactyly of a triphalangeal thumb
- synpolydactyly type 1
- triphalangeal thumb-polysyndactyly syndrome
- hallux varus-preaxial polysyndactyly syndrome
- symphalangism with multiple anomalies of hands and feet
- aphalangy-syndactyly-microcephaly syndrome
