SGTB
Description
The SGTB (small glutamine rich tetratricopeptide repeat co-chaperone beta) is a protein-coding gene located on chromosome 5.
SGTB is a co-chaperone that directly interacts with HSC70 and HSP70, influencing their ATPase activity.
SGTB is also known as SGT2.
Associated Diseases
- 46,XX ovotesticular disorder of sex development
- 46,XY complete gonadal dysgenesis
- testicular agenesis
- caudal duplication
- 46,XY sex reversal 3
- Mayer-Rokitansky-Kuster-Hauser syndrome
- mullerian duct anomalies-limb anomalies syndrome
