SH3RF3

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Description

The SH3RF3 (SH3 domain containing ring finger 3) is a protein-coding gene located on chromosome 2.

SH3RF3 possesses E3 ubiquitin-protein ligase activity, a crucial function in regulating protein degradation.

SH3RF3 is also known as POSH2, SH3MD4.

Associated Diseases

• plasma fibronectin deficiency
• isolated asymptomatic elevation of creatine phosphokinase
• schizophrenia
• congenital lethal erythroderma
• cancer