SLC23A2
Description
The SLC23A2 (solute carrier family 23 member 2) is a protein-coding gene located on chromosome 20.
SLC23A2 is a gene that encodes a protein involved in the absorption and distribution of vitamin C in the body. This protein is one of two transporters responsible for vitamin C uptake, and it plays a key role in tissue-specific vitamin C absorption. The gene was previously known as SLC23A1.
SLC23A2 is a sodium/ascorbate cotransporter that facilitates the electrogenic uptake of vitamin C. It transports two sodium ions (Na+) for every ascorbate molecule.
SLC23A2 is also known as NBTL1, SLC23A1, SVCT2, YSPL2.
Associated Diseases
- glucocorticoid-remediable aldosteronism
- congenital afibrinogenemia
- congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency
- cancer
