SLC44A2


Description

The SLC44A2 (solute carrier family 44 member 2 (CTL2 blood group)) is a protein-coding gene located on chromosome 19.

Choline transporter-like protein 2 is a protein that in humans is encoded by the SLC44A2 gene.

Choline/H+ antiporter, mainly located in mitochondria (PubMed:10677542, PubMed:20665236, PubMed:33789160, PubMed:23651124). It also functions as a low-affinity ethanolamine/H+ antiporter, regulating extracellular ethanolamine (Etn) supply for the CDP-Etn pathway. Additionally, it redistributes intracellular Etn and balances the CDP-Cho and CDP-Etn arms of the Kennedy pathway (PubMed:33789160).

SLC44A2 is also known as CTL2, PP1292.

Associated Diseases


Disclaimer

The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.