SLITRK5
Description
The SLITRK5 (SLIT and NTRK like family member 5) is a protein-coding gene located on chromosome 13.
SLIT and NTRK-like protein 5 is a protein found in humans that is encoded by the SLITRK5 gene. SLITRK5 is a transmembrane protein with two N-terminal leucine-rich repeat (LRR) domains similar to those found in SLIT proteins. Like most SLITRKs, SLITRK5 also has C-terminal regions that share similarities with neurotrophin receptors.
Inhibits the growth of nerve cell extensions (neurites).
SLITRK5 is also known as LRRC11, bA364G4.2.
Associated Diseases
- trichodysplasia-xeroderma syndrome
- immunodeficiency 75
- immunodeficiency 107, susceptibility to invasive staphylococcus aureus infection
- trichotillomania
- diffuse nonepidermolytic palmoplantar keratoderma
- colorectal cancer
- cystic fibrosis
