SMAD3
The SMAD3 gene builds a protein in a pathway controlling cell growth and development. Mutations in SMAD3 can disrupt this pathway, leading to conditions like Loeys-Dietz Syndrome (connective tissue problems) and Familial Thoracic Aortic Aneurysm and Dissection (weakening and tearing of the aorta).
Associated Diseases
Loeys-Dietz Syndrome and Familial Thoracic Aortic Aneurysm and Dissection
Did you know
SMAD3 might play a part in various processes like regulating cell proliferation, cancer development, and even heart function. Ongoing research is exploring these connections.
