SYNPO
Description
The SYNPO (synaptopodin) is a protein-coding gene located on chromosome 5.
Synaptopodin is a protein that in humans is encoded by the SYNPO gene. Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997).[supplied by OMIM] SYNPO has been shown to interact with MAGI1.
SYNPO is also known as SYNPO1.
Associated Diseases
- familial idiopathic steroid-resistant nephrotic syndrome
- acute kidney failure
- cancer
- type 2 diabetes mellitus
- Melnick-Needles syndrome
