TBX10
Description
The TBX10 (T-box transcription factor 10) is a protein-coding gene located on chromosome 11.
TBX10 is a gene that encodes a protein called T-box protein 10. This protein is a transcription factor, which means it can bind to DNA and regulate the expression of other genes. TBX10 is involved in a variety of developmental processes, including the formation of the heart, lungs, and limbs. Mutations in the TBX10 gene can lead to a number of developmental defects, including Holt-Oram syndrome, which is characterized by abnormalities of the heart and upper limbs.
TBX10 is also known as TBX13, TBX7.
Associated Diseases
- ankyloblepharon filiforme adnatum-cleft palate syndrome
- orofacial cleft 10
- orofacial cleft 5
- orofacial cleft 11
- van der Woude syndrome
- familial median cleft of the upper and lower lips
- cleft palate-lateral synechia syndrome
- van der Woude syndrome 1
- congenital laryngomalacia
- bifid uvula
- Pai syndrome
- Bencze syndrome
- Tessier number 4 facial cleft
- cleft palate with or without ankyloglossia, X-linked
- lethal omphalocele-cleft palate syndrome
