TCERG1
Description
The TCERG1 (transcription elongation regulator 1) is a protein-coding gene located on chromosome 5.
TCERG1 (Transcription elongation regulator 1) is a protein encoded by the TCERG1 gene in humans. It resides in the nucleus and plays a role in regulating both transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the phosphorylated C-terminal domain of RNA polymerase II through its multiple FF domains and with the pre-mRNA splicing factor SF1 via its WW domain. Different isoforms of TCERG1 are produced through alternative splicing.
TCERG1 is also known as CA150, TAF2S, Urn1.
Associated Diseases
- colorectal cancer
- Huntington disease
- cancer
- Alzheimer disease
- essential hypertension
- hemorrhagic disease
- Parkinson disease
- myelofibrosis
