TMEM150A

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Description

The TMEM150A (transmembrane protein 150A) is a protein-coding gene located on chromosome 2.

TMEM150A regulates the localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, potentially by reducing the interaction of TTC7 (TTC7A or TTC7B) with the PI4K complex (PubMed:25608530). It serves as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:25608530). TMEM150A might also be involved in fasting-induced catabolism (By similarity). {ECO:0000250|UniProtKB:Q9QZE9, ECO:0000269|PubMed:25608530}

TMEM150A is also known as TM6P1, TMEM150, TTN1.

Associated Diseases

• MYH7-related skeletal myopathy