UBXN7

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Description

The UBXN7 (UBX domain protein 7) is a protein-coding gene located on chromosome 3.

UBXN7 acts as a molecular bridge, connecting a specific group of NEDD8-modified cullin ring ligases (CRLs) to the protein-disassembly machine VCP/p97. This connection plays a crucial role in regulating the breakdown of proteins that have been tagged for destruction by ubiquitination.

UBXN7 is also known as UBXD7.

Associated Diseases

• breast cancer