YBX3
Description
The YBX3 (Y-box binding protein 3) is a protein-coding gene located on chromosome 12.
YBX3 binds to the GM-CSF promoter, suggesting a role in repressing gene expression. It also interacts with mRNA, specifically with full-length mRNA and short sequences containing the motif 5'-UCCAUCA-3'. This interaction might be involved in translation repression.
YBX3 is also known as CSDA, CSDA1, DBPA, ZONAB.
Associated Diseases
- partial chromosome Y deletion
- breast cancer
- cancer
- nonpapillary renal cell carcinoma
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failure 25
- spermatogenic failures 50
- congenital bilateral absence of vas deferens
- spermatogenic failure, X-linked, 2
- spermatogenic failure 63
- spermatogenic failure 48
- isochromosomy Yp
- spermatogenic failure 74
- spermatogenic failure 73
- spermatogenic failure 61
