ZBTB8OS

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Description

The ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand) is a protein-coding gene located on chromosome 1.

ZBTB8OS is part of the tRNA-splicing ligase complex, playing a crucial role in the enzymatic recycling of the catalytic subunit RTCB. It collaborates with DDX1 to facilitate the guanylylation of RTCB, a vital step in the tRNA ligation process.

ZBTB8OS is also known as ARCH, ARCH2.

Associated Diseases

• cancer
• pancreatic ductal adenocarcinoma