ZNF350
Description
The ZNF350 (zinc finger protein 350) is a protein-coding gene located on chromosome 19.
ZNF350 is a protein encoded by the ZNF350 gene in humans. It has been shown to interact with the BRCA1 protein.
ZNF350 acts as a transcriptional repressor by binding to a specific DNA sequence, 5‘-GGGxxxCAGxxxTTT-3‘, located within the third intron of the GADD45 gene.
ZNF350 is also known as ZBRK1, ZFQR.
Associated Diseases
- breast cancer
- cancer
- osteoporosis-pseudoglioma syndrome
- nonpapillary renal cell carcinoma
- osteogenesis imperfecta
