ZNF354C

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Description

The ZNF354C (zinc finger protein 354C) is a protein-coding gene located on chromosome 5.

ZNF354C acts as a transcriptional repressor that inhibits endothelial angiogenic sprouting. It suppresses the osteogenic effects of RUNX2 and may play a role in osteoblastic differentiation. ZNF354C is involved in postnatal myogenesis and may regulate satellite cell self-renewal.

ZNF354C is also known as KID3.

Associated Diseases

• microphthalmia with limb anomalies
• cancer