ZNF418

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Description

The ZNF418 (zinc finger protein 418) is a protein-coding gene located on chromosome 19.

ZNF418 acts as a transcriptional repressor, potentially regulating the ubiquitin-proteasome system and autophagy-lysosomal pathway. This function is supported by experimental evidence from UniProtKB:Q8BFS8 and PubMed:18084723.

ZNF418 is also known as ZFP418.

Associated Diseases

• popliteal pterygium syndrome
• nonpapillary renal cell carcinoma
• Peters plus syndrome