ZNF518A

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Description

The ZNF518A (zinc finger protein 518A) is a protein-coding gene located on chromosome 10.

ZNF518A participates in gene silencing by interacting with two histone methyltransferase complexes: EHMT1-EHMT2/G9A and PRC2/EED-EZH2. This interaction allows ZNF518A to regulate the methylation of histone tails at the promoters of target genes, leading to gene silencing.

ZNF518A is also known as ZNF518.

Associated Diseases

• substance abuse
• type 1 diabetes mellitus
• nemaline myopathy 5
• hereditary angioedema
• sarcoidosis